IMMEDIATELY AVAIABLE POSTDOC FELLOWSHIPS IN COMPUTATIONAL QUANTUM CHEMISTRY OF Metalloenzymes

 

The PostDoc Positions

Are immediately available

and will remain open until filled.



Address for contact:

Professor Sason Shaik
Department of Organic Chemistry and The LISE MEITNER-MINERVA CENTER for Computational Quantum Chemistry

Hebrew University 91904, Jerusalem ISRAEL



FAX +972(2)6584680
E-mail: sason@yfaat.ch.huji.ac.il
WWW home page http://yfaat.ch.huji.ac.il/sason.html



Structure and Reactivity of Metallo-Enzymes, Model Organometallics and Catalysts:

- Reactivity of Cytochrome P-450 and related enzymes which perform important oxidations (HRP, SAMO, NOS).

- The concept of chameleon catalysts that change their reactivity in accord with the hydrogen bonding capability and electrostatic field of the protein environment.

- Reactivity of catalysts which activate H2O2 to perform oxidation.

- Reactivity of oxometallates.


See for example recent papers: J. Am. Chem. Soc. 122, 8977 (2000) , J. Am. Chem. Soc. 122, 12892 (2000), J. Am. Chem. Soc., 123, 3037 (2001), Angew. Chem. Int. Ed. 40, 2874 (2001), Angew. Chem. Int. 41, 1947-1951 (2002), J. Am. Chem Soc,  124, 11809-11826 (2002). J. Am. Chem. Soc. 124, 8142-8151 (2002). Curr. Opinion Chem. Biol., 6, 556-567 (2002). J. Am. Chem. Soc., 126, 4017-4034 (2004). J. Am. Chem. Soc., 124, 8142-8151 (2002). J. Am. Chem Soc., 124, 2291-2300 (2003). J. Am. Chem Soc.,  124, 11809-11826 (2002). Angew. Chem. Int., 41, 1947-1951 (2002). J. Am. Chem. Soc., 125, 8698-8699 (2003). Eur. J. Inorg. Chem., 207-226 (2004). Angew. Chem. Int. Ed., 43, 1149-1152 (2004).

- Methods: MO and DFT-based methods. QM/MM methods are also planed.

Specifications: Send CV, list of publications, and names/addresses/e-mail addresses for at least two references. For all Candidates: Fluency in English is essential including scientific writing skills.